Detalhe da pesquisa
1.
Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix.
Proc Natl Acad Sci U S A
; 121(17): e2321898121, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38625939
2.
Preclinical efficacy of RAF/MEK clamp avutometinib in combination with FAK inhibition in low grade serous ovarian cancer.
Gynecol Oncol
; 2024 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493021
3.
Preclinical in vitro and in vivo activity of the RAF/MEK clamp avutometinib in combination with FAK inhibition in uterine carcinosarcomas.
Gynecol Oncol
; 187: 12-20, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38703673
4.
Elimusertib (BAY1895344), a novel ATR inhibitor, demonstrates in vivo activity in ATRX mutated models of uterine leiomyosarcoma.
Gynecol Oncol
; 168: 157-165, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36442427
5.
Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/neu expression.
Gynecol Oncol
; 170: 38-45, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36610380
6.
The Poly (ADP-ribose) polymerase inhibitor olaparib and pan-ErbB inhibitor neratinib are highly synergistic in HER2 overexpressing epithelial ovarian carcinoma in vitro and in vivo.
Gynecol Oncol
; 170: 172-178, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36706643
7.
Ovarian and uterine carcinosarcomas are sensitive in vitro and in vivo to elimusertib, a novel ataxia-telangiectasia and Rad3-related (ATR) kinase inhibitor.
Gynecol Oncol
; 169: 98-105, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36525930
8.
Uterine leiomyosarcomas harboring MAP2K4 gene amplification are sensitive in vivo to PLX8725, a novel MAP2K4 inhibitor.
Gynecol Oncol
; 172: 65-71, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36958197
9.
In vivo modeling of metastatic human high-grade serous ovarian cancer in mice.
PLoS Genet
; 16(6): e1008808, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32497036
10.
Monitoring Treatment Response, Early Recurrence, and Survival in Uterine Serous Carcinoma and Carcinosarcoma Patients Using Personalized Circulating Tumor DNA Biomarkers.
Int J Mol Sci
; 24(10)2023 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37240216
11.
Homologous recombination deficiency (HRD) signature-3 in ovarian and uterine carcinosarcomas correlates with preclinical sensitivity to Olaparib, a poly (adenosine diphosphate [ADP]- ribose) polymerase (PARP) inhibitor.
Gynecol Oncol
; 166(1): 117-125, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35599167
12.
Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors.
Proc Natl Acad Sci U S A
; 116(2): 619-624, 2019 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30584090
13.
Protein kinase Cα-mediated phosphorylation of Twist1 at Ser-144 prevents Twist1 ubiquitination and stabilizes it.
J Biol Chem
; 294(13): 5082-5093, 2019 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30733340
14.
Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA.
Mol Cancer
; 19(1): 143, 2020 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32928232
15.
Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription.
Mol Pharmacol
; 96(2): 168-179, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31175180
16.
Tumor microenvironment and immunology of ovarian cancer: 12th Biennial Rivkin Center Ovarian Cancer Research Symposium.
Int J Gynecol Cancer
; 29(Suppl 2): s12-s15, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31462543
17.
Corrigendum to "Elimusertib (BAY1895344), a novel ATR inhibitor, demonstrates in vivo activity in ATRX mutated models of uterine leiomyosarcoma".
Gynecol Oncol
; 170: 334, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36906375
18.
Harnessing small extracellular vesicles for pro-oxidant delivery: novel approach for drug-sensitive and resistant cancer therapy.
J Control Release
; 365: 286-300, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37992875
19.
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8.
Sci Adv
; 9(5): eade9585, 2023 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36724221
20.
In Vivo and In Vitro Efficacy of Trastuzumab Deruxtecan in Uterine Serous Carcinoma.
Mol Cancer Ther
; 22(12): 1404-1412, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37676984